FogCreek Software just released CityDesk version 2.0. As I've mentioned here previously, I used the beta and first release of CityDesk for a couple of sites, including this one. I eventually moved to MovableType, but still use CityDesk for one site. It's a nice client-side solution that doesn't require any special server software (just an FTP publish location).
CityDesk 2.0
Mobile Websites
As a side project, I maintain a popular list of mobile websites on cantoni.mobi.